BioGX Expands PCR Test Menu at State Departments of Health

BIRMINGHAM, AL / January 11, 2024 / BioGX, a leading global provider of easy molecular diagnostic solutions, is pleased to announce the test menu expansion support to Departments of Health (DoH) with the addition of its Candida auris assay. BioGX currently services 6 DoH agencies with expansion to 10 agencies expected in Q1 2024.

“We are excited to support the state Departments of Health by providing menu expansion solutions to meet stringent assay performance requirements,” said Shahin Iqbal, PhD, BioGX President & COO. “Our goal is to empower healthcare professionals with the best tools available, and this expansion is a testament to our commitment to improving public health outcomes in the region.”

As healthcare continues to evolve, the importance of robust and accurate diagnostic solutions has never been more critical. BioGX is committed to providing innovative and reliable molecular diagnostics solutions to support public health initiatives. State health departments play a pivotal role in safeguarding public health, requiring cutting-edge molecular diagnostics to quickly respond to the ever-changing landscape of testing needs.

View Original Press Release at:

https://www.newswire.com/news/biogx-expands-pcr-test-menu-at-state-departments-of-health-22217907

Microbix & BioGX Collaborate on real-time PCR Assays & Controls

Quality Controls for Respiratory Viral, Pharyngitis, and Genital Ulcer Disease Panels

Microbix Biosystems Inc. (TSX: MBX, OTCQX: MBXBF, Microbix®), a life sciences innovator, manufacturer, and exporter, announces a collaboration with BioGX, Inc. (“BioGX”), a global provider of easy molecular diagnostic solutions. The companies are collaborating to make Microbix’s Quality Assessment Products (“QAPs™”) available to BioGX Xfree™ customers that perform tests on the portable BioGX pixl™ real-time PCR platform, and other systems such as the Applied Biosystems QuantStudio™ 5 and 7500 Fast Dx, the BD MAX™, and the Bio-Rad CFX96 Touch™ and CFX384 Touch™.

Microbix was chosen by BioGX to be the primary External Quality Controls provider for assays on their newly-launched pixl platform – a benchtop instrument with capabilities for syndromic testing. To date, BioGX recommends nine PROCEEDx™ FLOQ® QAPs to be used in conjunction with assays that detect a wide variety of infectious organisms, including but not limited to SARS-CoV-2 (COVID), Influenza A&B (Flu), Group A Streptococcus (Strep), Herpes Simplex Virus 1&2 (Herpes), Varicella Zoster Virus (Chicken Pox), Treponema pallidum (Syphilis), and Mpox virus (Monkeypox).

Microbix QAPs are now referenced in BioGX Assay Product Inserts (available at https://www.biogx.com), with additional QAPs to be referenced as the collaboration expands. Microbix’s current QAPs catalogue is available on its website at https://microbix.com/request-catalogue/.

Xfree technology provides a complete lyophilized test in a single tube using the trusted BioGX Sample-Ready™ format for extraction-free, direct sample addition in real-time PCR testing. This format eliminates pre-treatment and nucleic-acid extraction steps, enabling labs with a simple Sample-to-Answer workflow. The tests can be shipped anywhere in the world without refrigeration.

Phil Casselli, SVP of Sales & Business Development at Microbix, commented, “It has been a pleasure to work with Robert and his team at BioGX to support their customer base with robust External Quality Controls. They selected our unique FLOQSwab® based QAPs because they replicate a patient specimen closely, are extremely convenient to ship, store, and use, and allow end-users to monitor their entire diagnostic workflow from sample collection to result.”

Robert Martinez, VP of Business Development & Scientific Affairs at BioGX, also commented, “We considered other external quality controls, but selected Microbix QAPs as the best solution to support assay optimization and to significantly simplify QC procedures with minimal to no pipetting steps. Microbix’s technical expertise, product design, performance, and superior customer service are impressive. We look forward to continuing our collaboration.”

About BioGX, Inc.BioGX is a leading global provider of lyophilized real-time PCR reagents for molecular diagnostics. BioGX, Inc., headquartered in Birmingham, Alabama and Dallas, TX, and its wholly owned subsidiary BioGX B.V., based in Amsterdam, The Netherlands, (collectively “BioGX”), operates in a cGMP compliant environment certified to ISO 13485 medical device development and manufacturing standards. The proprietary Sample-Ready™ technology is at the core of all product offerings for Clinical, Food Safety, Pharma QC and Water Quality molecular testing. BioGX’s 60+ multiplex real-time PCR products are marketed and sold in several countries through its Global Distribution Network.

About Microbix Biosystems Inc.Microbix Biosystems Inc. creates proprietary biological products for human health, with over 100 skilled employees and annualized sales targeting C$ 2.0 million per month. It makes a wide range of critical ingredients and devices for the global diagnostics industry, notably antigens for immunoassays and its laboratory quality assessment products (QAPs™) that support clinical lab proficiency testing, enable assay development and validation, or help ensure the quality of clinical diagnostic workflows. Its antigens drive the antibody tests of approximately 100 diagnostics makers, while QAPs are sold to clinical lab accreditation organizations, diagnostics companies, and clinical labs. Microbix QAPs are now available in over 30 countries, supported by a network of 10 international distributors. Microbix is ISO 9001 & 13485 accredited, U.S. FDA registered, Australian TGA registered, Health Canada establishment licensed, and provides CE marked products.

BioGX Expands Xfree Respiratory PCR With COVID-19/Flu A/Flu B Multiplex, Group A Streptococcus, Mycoplasma Pneumoniae

BIRMINGHAM, AL / ACCESSWIRE / September 7, 2023 / BioGX, a global provider of molecular diagnostic solutions, announces the availability of three new Xfree™ Direct-Sample-to-Answer PCR multiplexes for the detection of Group A Streptococcus, Mycoplasma pneumoniae and Flu A, Flu B, COVID-19 N1/RdRp. Xfree Flu A, Flu B, COVID-19 and Group A Streptococcus were previously CE-IVD marked while Mycoplasma pneumoniae is available as research use only. Laboratories can request custom manufactured formats for high-throughput use that may be validated for their intended use on a variety of real-time PCR platforms including, the BioGX pixl™, Applied Biosystems 7500, ThermoFisher QuantStudio and Bio-Rad CFX Touch.

“Our Xfree chemistry has proven to be highly robust in our FDA-EUA COVID-19 test. We are excited to offer expanded respiratory panels to equip our customers with cost-effective, rapid PCR workflows,” said Shahin Iqbal, Ph.D., President & COO of BioGX.

Xfree technology provides a complete lyophilized test in a single tube in the trusted BioGX Sample-Ready™ format for extraction-free, direct sample addition real-time PCR testing. This format eliminates pre-treatment and nucleic acid extraction steps, enabling labs with a simple Sample-to-Answer workflow. The test can be shipped anywhere in the world without refrigeration.

View Original Press Release at:

https://www.newswire.com/news/biogx-expands-xfree-respiratory-pcr-with-covid-19-flu-a-flu-b-22122287

BioGX Candida Auris PCR Assay Global Adoption Accelerates

BIRMINGHAM, Ala., July 23, 2023 (Newswire.com) – BioGX, a global provider of easy molecular diagnostic solutions, announced accelerated adoption of their high performance Sample-Ready™ PCR assay* for detection of Candida auris, a rapidly spreading, hard to treat fungus with a growing presence in hospitals and long-term care facilities. A complete PCR mix is provided in a single lyophilized tube format to be validated by laboratories on a variety of real-time PCR instruments including the BD MAX, ThermoFisher QuantStudio, BioRAD CFX Touch and the new BioGX pixl™ platform.

“Our platform agnostic Candida auris PCR assay has been successfully validated and implemented by numerous public health laboratories and hospitals,” said Shahin Iqbal, PhD, BioGX President & COO.” He further added, “We are grateful that laboratories trust us to address their unmet needs for detection of emerging pathogens.”

Dr. Margie Morgan, Director, Clinical Microbiology Pathology and Laboratory Medicine at Cedars Sinai Hospital in California said “the BioGX Candida auris PCR assay provides a rapid and sensitive method to perform surveillance testing for our patient population. The real time results have been used by our Epidemiology team to institute timely isolation precautions to successfully prevent C. auris transmission in our medical center.”

BioGX’s Sample-Ready™ line of products offer custom manufactured or Research Use Only PCR assays, lyophilized in a single vial and fine-tuned to ensure high performance across multiple platforms that are commonly used in laboratories today.

 

*Research Use Only, Not intended for human or animal diagnostic use.

Sample-Ready, Just Add Water, Xfree and pixl are trademarks of BioGX, Inc.

 

View Original Press Release at:

https://www.newswire.com/news/biogx-candida-auris-pcr-assay-global-adoption-accelerates-22089008

BioGX Candida auris PCR Assay Adoption Accelerates

BIRMINGHAM, Ala., March 23, 2023 (Newswire.com) – BioGX, a global provider of easy molecular diagnostic solutions, announced accelerated adoption of their high performance Sample-Ready™ PCR assay* for detection of Candida auris, a rapidly spreading, hard to treat fungus with a growing presence in hospitals and long-term care facilities. A complete PCR mix is provided in a single lyophilized tube format to be validated by laboratories on a variety of real-time PCR instruments including the BD MAX™, ThermoFisher QuantStudio™, BioRAD CFX Touch™ and the new BioGX pixl™ platform.

“Our platform agnostic Candida auris PCR assay has been successfully validated and implemented by public health laboratories and hospitals in several states,” said Shahin Iqbal, PhD, BioGX President & COO.” He further added, “We are grateful that laboratories trust us to address their unmet needs for detection of emerging pathogens.”

Dr. Margie Morgan, Director, Clinical Microbiology Pathology and Laboratory Medicine at Cedars Sinai Hospital said “the BioGX Candida auris PCR assay provides a rapid and sensitive method to perform surveillance testing for our patient population. The real time results have been used by our Epidemiology team to institute timely isolation precautions to successfully prevent C. auris transmission in our medical center.”

BioGX’s Sample-Ready™ line of products offer custom manufactured or Research Use Only PCR assays, lyophilized in a single vial and fine-tuned to ensure high performance across multiple platforms that are commonly used in laboratories today.

 

*Research Use Only, Not intended for human or animal diagnostic use.

 

View Original Press Release at:

https://www.newswire.com/news/biogx-candida-auris-pcr-assay-adoption-accelerates-21991160

BioGX Ships First Batch of pixl™ Real-Time PCR Platform to US Laboratories

BIRMINGHAM, Ala., February 28, 2023 (Newswire.com) – BioGX, a global provider of easy molecular diagnostic solutions since 2007, has announced fulfillment of multiple initial orders for its portable pixl™ real-time PCR platform to customers across the U.S., with immediate plans to scale production to meet market demand.

“We’re very impressed with the response to the launch of our novel ‘pixl’ qPCR platform. Pixl is accelerating validation and adoption of our vast multiplex RUO syndromic panels available in our unique Xfree and Sample-Ready lyophilized formats,” said Shazi Iqbal, Ph.D., BioGX CEO.

The pixl instrument is a compact, 4-channel, 16-well, real-time-PCR instrument that supports rapid turnaround times for batches of up to 16 samples, with integrated results analysis. Previously, in 2022, the US FDA authorized the pixl platform use with the BioGX Xfree COVID-19 Direct RT-PCR EUA test.

BioGX offers an extensive menu of RUO lyophilized multiplex syndromic panels for laboratory validation on the pixl platform, including the extraction-free Direct-Sample-to-Answer assays: Xfree Human Monkeypox (hMPXV), Xfree HSV1/HSV2/VZV and Xfree Treponema pallidum (Syphilis). The Xfree assay format is compatible with most transport/collection media types and can be validated for a wide variety of clinical sample collections.

View Original Press Release at:

https://www.newswire.com/news/biogx-ships-first-batch-of-pixl-real-time-pcr-platform-to-us-21969098

BioGX Launches ‘pixl™’ Portable qPCR Platform Ex-US With Expanded Test Menu for Infectious Diseases

BIRMINGHAM, Ala., December 8, 2022 (Newswire.com) – BioGX, a global provider of easy molecular diagnostic solutions since 2007, announced the Ex-US commercial release of its portable pixl™ qPCR real-time PCR platform for use with BioGX CE-IVD marked assays, enabling global access and complementing the recent US FDA EUA expanded use of Xfree™ COVID-19 Direct RT-PCR on the pixl.

The pixl instrument is a benchtop 4-channel, 16-well, RT-PCR instrument that supports rapid turnaround times for batches of up to 16 samples, with integrated results interpretation on a device with the compact footprint of a touchpad.

“pixl, combined with our unique Xfree chemistry, offers a low-cost direct-sample-to-answer PCR solution on a portable, compact device. pixl will provide broader access to clinical laboratories for decentralized PCR testing, enabling faster, better, low-cost near-patient molecular diagnostics,” said Shazi Iqbal, Ph.D., CEO of BioGX.

This platform was previously CE-IVD marked and can be used with the following BioGX CE-IVD marked assays:

  • Xfree COVID-19 (N1-gene) Direct RT-PCR
  • Xfree COVID-19 (N1/RdRp), Flu A, Flu B
  • Xfree Group A Streptococcus

Starting January 2023, BioGX will make additional syndromic tests available on the pixl platform from its large menu of lyophilized multiplex assays, including the Research Use Only (RUO) Direct-Sample assays: Xfree Human Monkeypox (hMPXV), Xfree HSV1/HSV2/VZV and Xfree Treponema pallidum (Syphilis). The Xfree assay format is compatible with most commonly used transport/collection media types and can be validated with a wide variety of patient sample collections.

View Original Press Release at:

https://www.newswire.com/news/biogx-launches-pixl-portable-qpcr-platform-ex-us-with-expanded-test-21897292

BioGX Expands FDA EUA with pixl™ Portable qPCR System for its Direct-Sample COVID-19 Assay

Birmingham, Alabama, Nov 10, 2022 – BioGX, a global provider of easy molecular diagnostic solutions since 2007, announced that the US FDA has updated their original (June 29, 2021) Direct Sample XfreeTM COVID-19 Emergency Use Authorization to increase the shelf-life of the assay reagent to 15 months and expand its use to additional real-time PCR platforms, including BioGX’s pixlTM real-time PCR platform.

 

The innovative BioGX XfreeTM Direct RT-PCR product is offered as a complete lyophilized test in a single vial. Upon rehydration with water, the test enables extraction-free, direct patient sample addition to a PCR tube which can be run on the BioGX pixlTM platform, Bio Molecular Systems MIC instrument and a variety of ubiquitous, high-throughput real-time PCR platforms. The Xfree assay can accept a wide variety of patient sample collections and is compatible with most commonly used transport/collection media types.

 

“With the pixl platform, customers can now generate fast sample-to-answer results on a portable, compact device. We expect the expanded EUA to provide broader access to clinical laboratories for decentralized PCR-based testing, enabling faster, better, low cost near-patient molecular diagnosis,” said Shazi Iqbal, Ph.D., CEO of BioGX.

View Original Press Release at:

https://www.businesswire.com/news/home/20221110006045/en/BioGX-Expands-FDA-EUA-with-pixl%E2%84%A2-Portable-qPCR-System-for-its-Direct-Sample-COVID-19-Assay

BioGX Announces Availability of Xfree PCR Reagents for Monkeypox

BIRMINGHAM, Ala.–(BUSINESS WIRE)–To address the growing need for simplified, rapid testing for Monkeypox, BioGX, a global provider of easy molecular diagnostic solutions, announced availability of Xfree PCR reagents for Sample-to-Answer Direct Sample PCR on multiple real-time PCR platforms including BioGX’s rapid “pixl” platform.

Dr. Suzane Silbert, Director, Esoteric Testing/R&D and Microbiology Laboratories at Tampa General Hospital (TGH) said, “We validated the BioGX Xfree hMPXV/OPXV custom manufactured reagents as Laboratory Developed Test on two platforms, BioGX’s pixl real-time PCR instrument and another Sample-to-answer Open System platform. The test is robust and showed excellent performance on both platforms with pixl having an advantage of a small footprint and providing 3x faster results.” She further added, “Prior to sourcing the reagents from BioGX, TGH was sending tests to an external reference laboratory with much longer turnaround time and higher costs.”

“BioGX Monkeypox Xfree PCR reagents validated by TGH leverages the highly successful Xfree extraction-free direct sample testing chemistry that is also included in the BioGX EUA Xfree COVID-19 Direct RT-PCR test,” said Robert Martinez, Ph.D., Sr. Director of Scientific Affairs & Strategic Partnerships. He further noted, “BioGX Monkeypox reagents incorporate the US CDC primer/probe designs to detect West African and Central African (Congo Basin) clades of the Monkeypox virus, and separately screen for non-variola Orthopox viruses.”

BioGX’s Xfree Direct Sample PCR reagents offer the flexibility to validate testing using a direct swab collection at point-of-care or a swab sample collected in transport media such as Copan UTM®, Copan ESwab™, Viral Transport Media or Phosphate Buffered Saline, completely bypassing the need for additional equipment and consumables for sample processing and extraction, saving both time and money.

View Original Press Release at:

https://www.businesswire.com/news/home/20221020005913/en/BioGX-Announces-Availability-of-Xfree-PCR-Reagents-for-Monkeypox

BioGX Launches CE-IVD Marked Multi-gene COVID-19 Point-of-Care Test at AACC

CHICAGO–(BUSINESS WIRE)–BioGX, a global provider of easy molecular diagnostic solutions, announced the launch of a point-of-care (POC) CE-Marked, three gene multiplex COVID-19 test on its pixl platform.

The test utilizes BioGX’s highly successful Xfree direct sample testing chemistry that is included in its US FDA emergency use authorized Xfree COVID-19 Direct RT-PCR test. This new multi-gene COVID-19 test targets the N1, RdRp and M gene regions for greater redundancy in detecting SARS-CoV-2 emerging variants.

This innovative POC test is simple to use and only requires the addition of one drop of sample added directly to the freeze-dried Xfree chemistry.

The BioGX pixl16 is a small, portable, 4-channel, 16-well real-time PCR platform that supports turnaround times of less than an hour for up to 16 samples. Results interpretation and reporting are integrated within the easy-to-use touchpad-based pixl instrument.

“Pixl combined with our unique Xfree chemistry offers our customers the ease-of-use and affordability of antigen-based testing with the superior sensitivity and specificity of real-time PCR testing”, said Shazi Iqbal, CEO of BioGX.

Building upon the success of its Xfree direct sample addition technology, BioGX is developing a pipeline of Xfree-pixl tests that will enable simple and affordable POC PCR testing. As with all BioGX tests, the Xfree COVID-19 3-gene Direct Sample RT-PCR kits ship globally at ambient temperature.

About BioGX

BioGX is a leading global provider of lyophilized real-time PCR reagents for molecular diagnostics. BioGX, Inc., headquartered in Birmingham, Alabama and Dallas, TX, and its wholly owned subsidiary BioGX B.V., based in Amsterdam, The Netherlands, (collectively “BioGX”), operates in a cGMP compliant environment certified to ISO 13485 medical device development and manufacturing standards. The proprietary Sample-Ready™ technology is at the core of all product offerings for Clinical, Food Safety, Pharma QC and Water Quality molecular testing. BioGX’s 60+ multiplex real-time PCR products are marketed and sold in several countries through its Global Distribution Network.

View Original source at https://www.businesswire.com/news/home/20220727006080/en/BioGX-Launches-CE-IVD-Marked-Multi-gene-COVID-19-Point-of-Care-Test-at-AACC